Spielname	Konsole	Release
Shinobi III: Return of the Ninja Master	Mega Drive	1993
Side Pocket	Mega Drive	1992
Skeleton Krew	Mega Drive	April 1995
Skitchin'	Mega Drive	1993
Snake Rattle n' Roll	Mega Drive	1993
Soleil	Mega Drive	1994
Sonic & Knuckles	Mega Drive	November 1994
Sonic 3D: Flickies' Island	Mega Drive	November 1996
Sonic Spinball	Mega Drive	15. November 1993
Sonic the Hedgehog	Mega Drive	23. Juni 1991
Sonic the Hedgehog 2	Mega Drive	24. November 1992
Sonic the Hedgehog 3	Mega Drive	Januar 1993
Space Harrier II	Mega Drive	1989
Sparkster	Mega Drive	1994
Speedball 2	Mega Drive	1990
Splatterhouse 2	Mega Drive	1992
Spot Goes To Hollywood	Mega Drive	Januar 1995
Star Control	Mega Drive	1991
Starflight	Mega Drive	1991
The Story of Thor	Mega Drive	März 1995
Street Fighter II': Special Champion Edition	Mega Drive	Oktober 1993
Street Racer	Mega Drive	1995
Streets of Rage	Mega Drive	1991
Streets of Rage 3	Mega Drive	1994
Streets of Rage II	Mega Drive	1993